50% DIE
Reduce deaths and improve outcomes for patients with heart failure
Leading causes of death
Deaths by percentage. Source: IHME, Global Burden of Disease, Our World in Data
Why?
Cardiovascular disease is rising by 2060 in the US alone
- Heart failure ≥ 33% – 12.9m
- Myocardial Infarction ≥ 30% – 16m
- Stroke ≥ 34% – 14.5m
As a result
- >~50,000 patients in the US alone present with cardiogenic shock per annum
- Up to 50% of them die within 30 days
- Current global mechanical circulatory support market is worth ~$2.5B with CAGR 21.6%
Target market per year
- >500,000 – Global
- 160,000 – US patients
- 60,000 – Cardiogenic shock
- 100,000 – Acute heart failure with low blood pressure